PacBio Revio HiFi: long‑read sequencing at scale for the most affordable HiFi genomes yet. With new SPRQ chemistry, Revio delivers richer, multiomic data with lower price per genome, making highly accurate long reads practical for large studies.

Now Available in Auckland, New Zealand.

Why choose Revio HiFi

Revio is a long‑read sequencing system designed to provide high‑throughput, highly accurate HiFi data for whole genomes, targets, epigenetics, and RNA on a single platform. HiFi reads from Revio offer long read lengths with 99.9% accuracy and uniform coverage, enabling reference‑quality assemblies and comprehensive variant detection. The system integrates powerful onboard compute, streamlined consumables, and new SPRQ‑Nx chemistry to reduce costs and add multiomic capabilities.

What does Revio offer?

Access more information at reduced cost and higher throughput, generating affordable HiFi genomes for large cohorts and population‑scale projects. Consolidate multiple assays into a single HiFi workflow that captures small variants, structural variants, repeat expansions, methylation, and full‑length transcripts. Benefit from highly accurate long reads with exceptional consensus accuracy and uniform coverage across the genome, even in hard‑to‑sequence regions. Enable multiomic studies with direct epigenetic detection and RNA sequencing on the same platform, powered by updated chemistries and application‑specific kits.

Applications

• Whole genome sequencing: achieve the highest consensus accuracy and uniform coverage for reference‑quality genomes in humans, plants, animals, and microbes.
• Targeted sequencing: accurately detect all variant types, including difficult repeat expansions and structural variants, even in hard‑to‑reach genomic regions.
• Epigenetics: explore how epigenetic changes, including DNA methylation, affect gene expression, host-pathogen interactions, and environmental response using native DNA.
• RNA sequencing: discover new genes, transcripts, and alternative splicing events with full‑length isoform sequencing, including high‑throughput workflows using the Kinnex full‑length RNA kit.

Revio long‑read sequencing enables you to access more genomic and epigenomic information at reduced cost and higher throughput on a single, integrated system.

From whole genomes and targeted panels to epigenetics and RNA, there's a HiFi solution for the questions that matter most in your research.